Why the disease has to sit on the line
US indications are neuropathic pain from diabetic peripheral neuropathy, postherpetic neuralgia, adjunct partial-onset seizures (age rules apply), fibromyalgia, and neuropathic pain from spinal cord injury. The 150 mg start is shared. The top is not.
A script that only says 'Lyrica 150 mg' without directions or a disease leaves the pharmacy guessing the split. Ask which row you are on.
What DPN does with 150 mg
Begin 50 mg three times daily (150 mg/day). The dose may rise to 300 mg/day within one week. Maximum recommended for DPN is 100 mg three times daily (300 mg/day) when CrCl is at least 60 mL/min.
600 mg/day was studied in DPN and did not add significant benefit; it was less well tolerated. Treatment above 300 mg/day is not recommended for that pain.
SCI pain and adult seizure adjunct
Spinal-cord injury pain starts at 75 mg twice daily (150 mg/day), may reach 300 mg/day within one week, and can go to 600 mg/day as 300 mg twice daily after 2 to 3 weeks at 300 if pain remains and the person tolerates it. That row is two divided doses.
Adult adjunct partial-onset seizures begin at 150 mg/day and may rise toward 600 mg/day in two or three doses. Pediatric dosing is weight-based and is not this adult 150 mg lock.
What PHN does with 150 mg
Begin 75 mg twice daily or 50 mg three times daily (150 mg/day). The dose may rise to 300 mg/day within one week. People who still hurt after 2 to 4 weeks at 300 and who tolerate the capsule may go toward 600 mg/day.
Reserve dosing above 300 mg/day for ongoing pain plus tolerance. Dose-dependent adverse reactions and higher dropout sit behind that reserve.
What fibromyalgia does with 150 mg
Begin 75 mg twice daily (150 mg/day). Rise to 150 mg twice daily (300 mg/day) within one week if needed. People who still lack benefit at 300 may go to 225 mg twice daily (450 mg/day).
600 mg/day was studied and did not add benefit; it was less well tolerated. Doses above 450 mg/day are not recommended for fibromyalgia.
Indication tag without mixing heights
Write the disease next to 150 mg. DPN 300. Fibro 450. PHN and SCI can see 600 in selected adults. Kidneys rewrite every ceiling. Kidney scan.
Yuki Tanaka tags the row after Dosage and Administration. Ankles still watched: edema watch.